Prothese-infecties - arthrodese/spondylodese
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: cefazoline iv 2000mg 3dd maximum 3 days |
Remarks:
Laag risico infectie of indien het kunstmateriaal verwijderd is Indien ontslag binnen 3 dagen: orale optie clindamycine 3 dd 600 mg |
|
Priority: 1st choice alternative |
Medication: vancomycine iv loading dose 20mg/kg, 40mg/kg continuous per 24 hours +
ciprofloxacine iv 400mg 3dd maximum 3 days |
Remarks:
Hoog risico infectie Maximale oplaaddosis vancomycine: 1500 mg Alternatief vancomycine: 20 mg/kg 2 dd, oplaaddosis 30 mg/kg tot een maximum van 1500 mg |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: flucloxacilline iv loading dose 2000g, 12g continuous per 24 hours 2 to 4 weeks +
rifampicine iv 450mg 2dd 2 to 4 weeks |
Remarks:
Initiele therapie |
|
Priority: 1st choice |
Medication: ciprofloxacine po 750mg 2dd maximum 3 months +
rifampicine po 450mg 2dd maximum 3 months |
Remarks:
Bij switch naar orale therapie Therapieduur in overleg |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: benzylpenicilline iv loading dose 2million. IU, 12million. IU continuous per 24 hours 2 to 4 weeks |
Remarks:
Initiele therapie |
|
Priority: 1st choice |
Medication: clindamycine po 600mg 3dd maximum 3 months |
Remarks:
Bij switch naar orale therapie Therapieduur in overleg
|
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: ciprofloxacine iv 400mg 3dd 2 to 4 weeks or
ceftriaxon iv 2g 1dd 2 to 4 weeks |
Remarks:
Initiele therapie |
|
Priority: 1st choice |
Medication: ciprofloxacine po 750mg 2dd maximum 3 months |
Remarks:
Bij switch naar orale therapie Therapieduur in overleg |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: ceftazidim iv 2000mg 3dd 2 to 4 weeks |
Remarks:
Initiële therapie |
|
Priority: 1st choice |
Medication: ciprofloxacine po 750mg 2dd maximum 3 months |
Remarks:
Bij switch naar orale therapie Therapieduur in overleg |
Sources
TDM Alert
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-446125.4
Updated: 12/05/2023 - 15:33
Status: Published
General comments
Behandeling is gebaseerd op zowel het orthopedisch beleid als geisoleerde micro-organismen. Antibiotische behandeling in overleg met arts-microbioloog.