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mediastinitis

Advices

≥ 18 years
Priority Medication Remarks
Medication:

ceftriaxon iv 2000mg 1dd 2 to 6 weeks

+

metronidazol iv 500mg 3dd 2 weeks

Remarks:

SWAB remarks

Na perforatie tr. digestivus: na manipulatie of ingreep. 

Medication:

flucloxacilline iv 1000mg 6dd 2 to 6 weeks

or

flucloxacilline iv loading dose 1000mg, 6000mg continuous per 24 hours 2 to 6 weeks

Remarks:

SWAB remarks

Postoperatief na sternotomie

General comments

Chirurgische drainage is de belangrijkste therapeutische handeling. Antibiotische therapie zal, indien nodig, gegeven worden op geleide van Grampreparaat en kweek. Een acute post-operatieve mediastinitis met sepsis zal vaak veroorzaakt worden door een Staphylococcus aureus.

Sources

  1. Pubmed.gov publication # 31306791

    Pastene B, et al. Mediastinitis in the intensive care unit patient: a narrative review. Clin Microbiol Infect. 2020 Jan;26(1):26-34.

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-8519.6
Updated: 02/03/2023 - 14:37
Status: Published