encephalitis - Herpes simplex
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Medication: aciclovir iv 10mg/kg 3dd 21 days |
Remarks:
Diakonessenhuis remarks Duur behandeling 14-21 dagen |
Sources
-
Pubmed.gov publication # 18582201
IDSA guideline: Tunkel AR, Glaser CA, Bloch KC, et al; Infectious Diseases Society of America. The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2008;47:303-27.
TDM Alert
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
Swab vid: G-7083.3
Updated: 02/03/2023 - 13:32
Status: Published
General comments
Bij obesitas (=BMI>30kg/m2) en dosering ≥ 10mg/kg (iv): om toxiciteit (m.n. nefro- en neurotoxiciteit) bij obese patiënten te voorkomen, doseer op basis van het “adjusted body weight” (zie: https://www.mdcalc.com/ideal-body-weight-adjusted-body-weight). Monitor na start urineproductie en dagelijks de nierfunctie.