ceftolozane / tazobactam
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DI - Other Cephalosporins -> J01DI54 - Zerbaxa
Administration category:
Limited
Medicine group:
antibacterial
File parts:
ceftolozane
tazobactam
Brand name:
Zerbaxa
Standard dosages
| Weight | ROA | Load | Dosage |
|---|---|---|---|
|
ROA: iv |
Load: - |
Dosage: 1000/500mg 3 dd |
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 30 - 50 |
Dosage: 500 mg ceftolozaan + 250 mg tazobactam |
Comments: 3 dd |
||
|
GFR: 15 - 30 |
Dosage: 250 mg ceftolozaan + 125 mg tazobactam |
Comments: 3 dd |
||
|
GFR: 5 - 15 |
Dosage: eenmalige oplaaddosis 500 mg ceftolozaan en 250 mg tazobactam, na 8 uur 100 mg ceftolozaan + 50 mg tazobactam 3 dd |
|||
Renal elimination:
95%
Dosage:
dependent on kidney function
Renal function-replacement therapy
Hemo dialysis: eenmalige oplaaddosis van 500 mg/250 mg gevolgd door een onderhoudsdosis van 100 mg/50 mg elke 8 uur. Op dagen van hemodialyse de dosis zo snel mogelijk na de hemodialyse toedienen
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-343511.1
Updated: 06/16/2020 - 16:40
Status: Published