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Endocarditis, natieve klep - Staphylococcus aureus

Advices

≥ 18 years
Priority Medication Remarks
Medication:

flucloxacilline iv loading dose 2000g, 12g continuous per 24 hours 6 weeks

≥ 18 years

Indications: Bij penicilline allergie

Priority Medication Remarks
Priority:
1st choice
Medication:

cefazoline iv 2g 3dd 6 weeks

Remarks:

Alternatief: cefazoline 6g continue per 24 uur, opladen met 2g

Priority:
1st choice
Medication:

vancomycine iv loading dose 20mg/kg, 40mg/kg continuous per 24 hours 6 weeks

Remarks:

Bij ernstige penicilline allergie

Maximale oplaaddosis vancomycine: 1500 mg

Alternatief vancomycine: 20 mg/kg 2 dd, oplaaddosis 30 mg/kg tot een maximum van 1500 mg

General comments

De totale duur van de behandeling is 6 weken. Pas de dosering van  vancomycine aan op geleide van spiegels.

Sources

TDM Alert
Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-205266.7
Updated: 04/14/2023 - 12:32
Status: Published