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norfloxacine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01M - Quinolone Antibacterials -> J01MA - Fluoroquinolones -> J01MA06 - Norfloxacin
Administration category: Free Medicine group: antibacterial Brand name: Noroxin

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
po
Dosage:
min. 400mg 1 dd to max. 400mg 3 dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: po
GFR:
10 - 30
Dosage:
400 mg
Interval:
24 Hours
GFR:
30 - 50
Dosage:
400 mg
Interval:
12 Hours
Renal elimination: 25%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Geef de normale keerdosis met een interval van 24 uur tussen 2 doses.

Hemo dialysis: Geef de normale keerdosis met een interval van 24 uur tussen 2 doses.

Interactions

Interaction with (ATC): Interaction with: Expected effect:
Interaction with (ATC):
Interaction with:
aluminium- of magnesiumzouten bevattende antacida
Expected effect:
vermindering absorptie norfloxacine
Interaction with (ATC):
Interaction with:
ijzerzouten
Expected effect:
vermindering absorptie norfloxacine
Interaction with (ATC):
R03DA04 - Theophylline
Interaction with:
Expected effect:
verhoging plasmaconcentratie theofylline
Interaction with (ATC):
A02BX02 - Sucralfate
Interaction with:
Expected effect:
vermindering absorptie norfloxacine

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1624.2
Updated: 06/16/2019 - 20:05
Status: Published

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