cefuroxim
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DC - Second-Generation Cephalosporins -> J01DC02 - Cefuroxime
Administration category:
Free
Medicine group:
antibacterial
Brand name:
Zinacef; Zinnat
Safety margins
| Weight | ROA | Dosage | |
|---|---|---|---|
|
ROA: po |
Dosage: min. 125mg 2 dd to max. 500mg 2 dd |
||
|
ROA: iv |
Dosage: min. 750mg 3 dd to max. 3000mg 3 dd |
||
|
ROA: iv |
Dosage: min. 2250mg to max. 4500mg continuous per 24 hours |
||
|
Comments:
bij continue infusie 1500 mg loading dose. Hogere doses indien geïndiceerd tot 9000 mg/24 uur |
|||
Dosage for "I" sensitivity
| Weight | ROA | Load | Dosage | |
|---|---|---|---|---|
|
ROA: iv |
Load: - |
Dosage: 1500mg 3 dd |
||
|
Comments:
NB: hoge dosering is zelfde als standaard dosering voor gram-negatieve bacteriën |
||||
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 10 - 30 |
Dosage: standaarddosering |
Interval: 12 Hours |
||
|
GFR: <10 |
Dosage: standaarddosering |
Interval: 24 Hours |
||
Renal elimination:
95%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: 750 mg 2 dd iv.
Hemo dialysis: 750 mg 2 dd iv, op dialysedagen tweede dosis na dialyse.
CAV / VVHD: Continue venoveneuze hemodialyse/hemo(dia)filtratie: 3 g continu of 1500 mg 3x per dag
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1215.10
Updated: 02/16/2024 - 16:44
Status: Published